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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LYRIC Antibody (1B982)

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货号 TMAB-08473

Anti-LYRIC Antibody (1B982) 是一种 Rabbit 抗体，靶向 LYRIC。Anti-LYRIC Antibody (1B982) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-LYRIC Antibody (1B982)

Anti-LYRIC Antibody (1B982)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08473

Anti-LYRIC Antibody (1B982) 是一种 Rabbit 抗体，靶向 LYRIC。Anti-LYRIC Antibody (1B982) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-LYRIC Antibody (1B982) is a Rabbit antibody targeting LYRIC. Anti-LYRIC Antibody (1B982) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
1B982
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Cell junction, tight junction. Nucleus, nucleolus . Cytoplasm, perinuclear region. Note=In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes. A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain. TNF-alpha causes translocation from the cytoplasm to the nucleus.
组织特异性Widely expressed with highest levels in muscle-dominating organs such as skeletal muscle, heart, tongue and small intestine and in endocrine glands such as thyroid and adrenal gland. Overexpressed in various cancers including breast, brain, prostate, melanoma and glioblastoma multiforme.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
抗原信息
免疫原
A synthesized peptide: human MTDH
抗原种属
Human
基因名称
MTDH
基因ID
92140
蛋白名称
Protein LYRIC
Uniprot ID
Q86UE4
功能
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
化学信息
分子量Theoretical: 64 kDa. Actual: 75 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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