Okadaic acid ammonium salt (0-100 nM; 24 h or 48 h) inhibits the proliferation of AGS, MNK-45, Caco 2 cells[3]. Okadaic acid (10 nM, 8 hours) ammonium salt increases Drp1 phosphorylation and mitochondrial fission in rat cortical neurons[4]. Cell Proliferation Assay[3]Cell Line: AGS, MNK-45 and Caco 2 cell lines Concentration: 0-100 nM Incubation Time: 24 h or 48 h Result: Inhibited the proliferation of AGS, MNK-45, Caco 2 cells.

Okadaic acid ammonium salt (100 μM; injected unilaterally to the lateral amygdala) induces Tau phosphorylation and protein aggregation in anatomically distinct brain regions 24 h post-injection[5]. Animal Model: Female wild-type C57BL/6 mice (6 to 8 months)[5]Dosage: 100 μM Administration: Injected unilaterally to the lateral amygdala Result: Induced Tau phosphorylation and protein aggregation in anatomically distinct brain regions 24 h post-injection.