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Anti-ALOX15 Polyclonal Antibody 2
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产品编号 TMAB-00099
Anti-ALOX15 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ALOX15。Anti-ALOX15 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-ALOX15 Polyclonal Antibody 2
Anti-ALOX15 Polyclonal Antibody 2
还可以产品编号 TMAB-00099
Anti-ALOX15 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ALOX15。Anti-ALOX15 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-ALOX15 Polyclonal Antibody 2 is a Rabbit antibody targeting ALOX15. Anti-ALOX15 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | Sample: Lane 1: A431 (Human) Cell Lysate at 30 μg Lane 2: Hela (Human) Cell Lysate at 30 μg Lane 3: A549 (Human) Cell Lysate at 30 μg Lane 4: HepG2 (Human) Cell Lysate at 30 μg Primary: Anti-ALOX15 (TMAB-00099) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75 kDa Observed band size: 77 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:10-50; IF: 1:10-50 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation. |
| 免疫原 | KLH conjugated synthetic peptide: human ALOX15 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Tumor biomarkers,Lipoprotein metabolism,Metabolism,Fatty acids,Lipoprotein metabolism,Fatty acid oxidation,Heart disease,Hormones |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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