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Anti-CD204/MSR1 Polyclonal Antibody
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产品编号 TMAB-00345
Anti-CD204/MSR1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD204/MSR1。Anti-CD204/MSR1 Polyclonal Antibody 可用于 WB。
Anti-CD204/MSR1 Polyclonal Antibody
Anti-CD204/MSR1 Polyclonal Antibody
还可以产品编号 TMAB-00345
Anti-CD204/MSR1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD204/MSR1。Anti-CD204/MSR1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
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抗原信息
| 产品描述 | Anti-CD204/MSR1 Polyclonal Antibody is a Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Mouse,Rat |
| 验证活性 | Sample: Lane 1: Spleen (Mouse) Lysate at 40 μg Lane 2: Lung (Mouse) Lysate at 40 μg Lane 3: Liver (Mouse) Lysate at 40 μg Lane 4: Placenta (Mouse) Lysate at 40 μg Lane 5: Cerebrum (Mouse) Lysate at 40 μg Lane 6: Raw264.7 (Mouse) Cell Lysate at 30 μg Lane 7: NIH/3T3 (Mouse) Cell Lysate at 30 μg Lane 8: Liver (Rat) Lysate at 40 μg Lane 9: Cerebrum (Rat) Lysate at 40 μg Primary: Anti-MSR1 (TMAB-00345) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50/39 kDa Observed band size: 50 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human MSR1/CD204 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Heart disease,Lipoprotein metabolism,Macrophage / Inflamm.,Innate and adaptive immunity,Lipoprotein metabolism |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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