Name: Posdinemab
Brand: TargetMol
SKU: T80616
Price: 2490 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 2,490

现货

5 mg

¥ 6,470

现货

10 mg

¥ 9,870

现货

生物活性

产品描述	Posdinemab (JNJ-63733657) is a humanized monoclonal antibody targeting pT217 phosphorylated Tau. By specifically binding to pathological Tau, it blocks its propagation and aggregation between neurons, thereby delaying the progression of Alzheimer's and other tauopathies.
体外活性	在人工脑脊液及小鼠脑匀浆实验中，通过 100 nM Posdinemab 结合免疫沉淀与 20 小时酶解处理，并利用 LC-MS 技术测得其能特异性富集含 pT217 位点的双磷酸化 Tau 肽段 (SRTPSLPTPPTREPK2p)，确证了该抗体对病理性磷酸化 Tau 蛋白具有极高的亲和力及精准的选择性捕获能力 [2]。
别名	JNJ-63733657, JNJ63733657, JNJ 63733657
反应种属	Human
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型	Human IgG1 kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

分子量	145.34 kDa
CAS No.	2517973-04-3

储存&溶解度

存储	Store at -20°C Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Posdinemab