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Anti-Cytokeratin 20 Antibody (2X563)

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货号 TMAB-04949

Anti-Cytokeratin 20 Antibody (2X563) 是一种 Mouse 抗体,靶向 Cytokeratin 20。Anti-Cytokeratin 20 Antibody (2X563) 可用于 IHC-P,IF,IHC-Fr。

Anti-Cytokeratin 20 Antibody (2X563)

Anti-Cytokeratin 20 Antibody (2X563)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04949

Anti-Cytokeratin 20 Antibody (2X563) 是一种 Mouse 抗体,靶向 Cytokeratin 20。Anti-Cytokeratin 20 Antibody (2X563) 可用于 IHC-P,IF,IHC-Fr。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍


生物活性
产品描述
Anti-Cytokeratin 20 Antibody (2X563) is a Mouse antibody targeting Cytokeratin 20. Anti-Cytokeratin 20 Antibody (2X563) can be used in IHC-P,IF,IHC-Fr.
Ig Type
IgG2b,k
克隆号
2X563
反应种属
Human,Mouse,Rat
应用IHC-PIFIHC-Fr
推荐剂量
IHC-P: 1:100-500; IF: 1:100-500; IHC-Fr: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm.
组织特异性Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300.
浓度1mg/ml
研究背景Cytokeratin 20 is a type I keratin which is primarily expressed in gastric and intestinal epithelium, urothelium, and Merkel-cells. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Their genes are clustered in a region of chromosome 17q12-q21. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. It is also expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system and is present in mucinous ovarian tumors, transitional-cell and Merkel-cell carcinomas. Notably, the squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas lack cytokeratin 20.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CK20
抗原种属
Human
基因名称
KRT20
基因ID
蛋白名称
Keratin, type I cytoskeletal 20
Uniprot ID
功能
Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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