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别名 TDRD16C, survival motor neuron domain containing 1, SPF30, SMNR
SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. SMNDC1 gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. SMNDC1 is necessary for spliceosome assembly. Its overexpression causes apoptosis.


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SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. SMNDC1 gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. SMNDC1 is necessary for spliceosome assembly. Its overexpression causes apoptosis.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 493 | 6-8日内发货 | |
| 10 μg | ¥ 790 | 6-8日内发货 | |
| 20 μg | ¥ 1,330 | 5日内发货 | |
| 50 μg | ¥ 2,580 | 5日内发货 | |
| 100 μg | ¥ 5,170 | 5日内发货 |
| 产品描述 | SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. SMNDC1 gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. SMNDC1 is necessary for spliceosome assembly. Its overexpression causes apoptosis. |
| 生物活性 | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. SMNDC1 gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. SMNDC1 is necessary for spliceosome assembly. Its overexpression causes apoptosis. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-His |
| 蛋白编号 | O75940 |
| 蛋白构建 | A DNA sequence encoding the mature form of human SMNDC1 (O75940) (Met1-Gln238) was expressed with a polyhistide tag at the N-terminus. Predicted N terminal: His |
| 蛋白纯度 | > 85 % as determined by SDS-PAGE |
| 蛋白性状 | Solution |
| 缓冲液 | Supplied as sterile PBS, 20% Glycerol, pH 7.4. |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 别名 | TDRD16C, survival motor neuron domain containing 1, SPF30, SMNR |
| 内毒素 | Please contact us for more information. |
| 分子量 | 28.5 kDa (predicted); 29 kDa (reducing conditions) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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