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Anti-Kallikrein 13/KLK13 Antibody (1E970) 是一种 Mouse 抗体,靶向 Kallikrein 13/KLK13。Anti-Kallikrein 13/KLK13 Antibody (1E970) 可用于 ELISA。
Anti-Kallikrein 13/KLK13 Antibody (1E970) 是一种 Mouse 抗体,靶向 Kallikrein 13/KLK13。Anti-Kallikrein 13/KLK13 Antibody (1E970) 可用于 ELISA。
产品描述 | Anti-Kallikrein 13/KLK13 Antibody (1E970) is a Mouse antibody targeting Kallikrein 13/KLK13. Anti-Kallikrein 13/KLK13 Antibody (1E970) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG2a |
克隆号 | 1E970 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KLK13 / Kallikrein13 (rhKLK13; TMPY-00867; NP_056411.1; Met 1-Ile 262). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers and is regarded as a novel cancer biomarker. Besides, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones. |
偶联 | Unconjugated |
免疫原 | Recombinant Human KLK13 protein (TMPY-00867) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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