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Anti-Alkaline Phosphatase/ALPL Antibody (3T684) 是一种 Rabbit 抗体,靶向 Alkaline Phosphatase/ALPL。Anti-Alkaline Phosphatase/ALPL Antibody (3T684) 可用于 IHC-P。
Anti-Alkaline Phosphatase/ALPL Antibody (3T684) 是一种 Rabbit 抗体,靶向 Alkaline Phosphatase/ALPL。Anti-Alkaline Phosphatase/ALPL Antibody (3T684) 可用于 IHC-P。
产品描述 | Anti-Alkaline Phosphatase/ALPL Antibody (3T684) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (3T684) can be used in IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3T684 |
交叉反应 | Human |
验证活性 | Immunochemical staining of human ALPL in human adrenal gland with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:250-1:1000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human Alkaline Phosphatase / ALPL. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment. It is sometimes used synonymously as basic phosphatase. Alkaline phosphatases (APs) are ubiquitous in many species, from bacteria to human. Four genes encode AP isoenzymes in humans and rodents. Three AP genes are expressed in a tissue-specific manner (i.e., placental, embryonic, and intestinal AP isoenzymes). Expression of the fourth AP gene is nonspecific to a single tissue and is especially abundant in bone, liver, and kidney. This isoenzyme is also called tissue-nonspecific alkaline phosphatase (TNAP). The enzyme tissue non-specific alkaline phosphatase (TNAP) belongs to the ectophosphatase family. TNAP is present in large amounts in bone in which it plays a role in mineralization. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide corresponding to the center region of the Human Alkaline Phosphatase / ALPL |
抗原种属 | Human |
研究领域 | Phosphatases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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