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Anti-Uteroglobin Antibody (7Q840)

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Anti-Uteroglobin Antibody (7Q840)
产品编号 TMAC-03693
别名 UP-1, SCGB1A1

Anti-Uteroglobin Antibody (7Q840) 是一种 Rabbit 抗体,靶向 Uteroglobin。Anti-Uteroglobin Antibody (7Q840) 可用于 WB,ICC,FCM。

Anti-Uteroglobin Antibody (7Q840)

Anti-Uteroglobin Antibody (7Q840)

Rating icon 还可以
Anti-Uteroglobin Antibody (7Q840)
产品编号 TMAC-03693 别名 UP-1, SCGB1A1

Anti-Uteroglobin Antibody (7Q840) 是一种 Rabbit 抗体,靶向 Uteroglobin。Anti-Uteroglobin Antibody (7Q840) 可用于 WB,ICC,FCM。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Uteroglobin Antibody (7Q840) is a Rabbit antibody targeting Uteroglobin. Anti-Uteroglobin Antibody (7Q840) can be used in WB,ICC,FCM.
别名UP-1, SCGB1A1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of SCGB1A1 on mouse lung tissue (1) and A549 cell (2) lysate using anti-SCGB1A1 antibody at 1/500 dilution.
2. ICC staining SCGB1A1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining SCGB1A1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining SCGB1A1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of A549 cells with SCGB1A1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
应用
推荐剂量
WB: 1:500-1000; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景SCGB1A1 also named CC10. Clara cell 10 (CC10) protein, a homologue of rabbit uteroglobin, is a phospholipase A2 inhibitor. CC10 is regulated by AP-1, octamer, and hepatocyte nuclear factor-3 (HNF-3) family transcription factors. CC10 expression changes in relation to the ovarian menstrual cycle, and expression in human endometrium may be stimulated by progesterone, suggesting that CC10 may regulate eicosanoid levels in the human uterus. CC10 is expressed in nonciliated airway epithelial cells in the lung and in urogenital secretions. CC10 is involved in modulating inflammation in airway passages and may play a role in asthma. Overexpression of CC10 in the non-small cell lung cancer cell line A549 was shown to result in the near absence of MMP-2 and MMP-9 matrix metalloproteinases and a reduction in invasiveness, indicating that loss of CC10 may contribute to carcinogenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 10 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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