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Anti-Uteroglobin Antibody (7Q840) 是一种 Rabbit 抗体,靶向 Uteroglobin。Anti-Uteroglobin Antibody (7Q840) 可用于 WB,ICC,FCM。
Anti-Uteroglobin Antibody (7Q840) 是一种 Rabbit 抗体,靶向 Uteroglobin。Anti-Uteroglobin Antibody (7Q840) 可用于 WB,ICC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-Uteroglobin Antibody (7Q840) is a Rabbit antibody targeting Uteroglobin. Anti-Uteroglobin Antibody (7Q840) can be used in WB,ICC,FCM. |
别名 | UP-1, SCGB1A1 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of SCGB1A1 on mouse lung tissue (1) and A549 cell (2) lysate using anti-SCGB1A1 antibody at 1/500 dilution. 2. ICC staining SCGB1A1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining SCGB1A1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining SCGB1A1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of A549 cells with SCGB1A1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
应用 | |
推荐剂量 | WB: 1:500-1000; ICC: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | SCGB1A1 also named CC10. Clara cell 10 (CC10) protein, a homologue of rabbit uteroglobin, is a phospholipase A2 inhibitor. CC10 is regulated by AP-1, octamer, and hepatocyte nuclear factor-3 (HNF-3) family transcription factors. CC10 expression changes in relation to the ovarian menstrual cycle, and expression in human endometrium may be stimulated by progesterone, suggesting that CC10 may regulate eicosanoid levels in the human uterus. CC10 is expressed in nonciliated airway epithelial cells in the lung and in urogenital secretions. CC10 is involved in modulating inflammation in airway passages and may play a role in asthma. Overexpression of CC10 in the non-small cell lung cancer cell line A549 was shown to result in the near absence of MMP-2 and MMP-9 matrix metalloproteinases and a reduction in invasiveness, indicating that loss of CC10 may contribute to carcinogenesis. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 10 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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