购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
顶部生物活性储存和溶解信息计算器

Anti-L1CAM Antibody (4G234)

Rating icon 还可以
Anti-L1CAM Antibody (4G234)
产品编号 TMAY-00336
别名 SPG1, S10, NCAM-L1, N-CAM-L1, N-CAML1, MIC5, MASA, L1 cell adhesion molecule, HSAS1, HSAS, CD171, CAML1

Anti-L1CAM Antibody (4G234) 是一种 Rabbit 抗体，靶向 L1CAM。Anti-L1CAM Antibody (4G234) 可用于 ELISA(Det),IHC-P,FCM,ICC/IF。

Anti-L1CAM Antibody (4G234)

Anti-L1CAM Antibody (4G234)

Rating icon 还可以
Anti-L1CAM Antibody (4G234)
产品编号 TMAY-00336 别名 SPG1, S10, NCAM-L1, N-CAM-L1, N-CAML1, MIC5, MASA, L1 cell adhesion molecule, HSAS1, HSAS, CD171, CAML1

Anti-L1CAM Antibody (4G234) 是一种 Rabbit 抗体，靶向 L1CAM。Anti-L1CAM Antibody (4G234) 可用于 ELISA(Det),IHC-P,FCM,ICC/IF。

规格价格库存数量
20 μL
¥ 785
5日内发货
100 μL
¥ 2,495
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-L1CAM Antibody (4G234) is a Rabbit antibody targeting L1CAM. Anti-L1CAM Antibody (4G234) can be used in ELISA(Det),IHC-P,FCM,ICC/IF.
别名SPG1, S10, NCAM-L1, N-CAM-L1, N-CAML1, MIC5, MASA, L1 cell adhesion molecule, HSAS1, HSAS, CD171, CAML1
Ig Type
Rabbit IgG
克隆号
4G234
交叉反应
Human
验证活性
1. Immunochemical staining of human CD171 in human appendix with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to myenteric nerve plexus.
2. Flow cytometric analysis of human CD171 expression on HeLa cells. Cells were stained with purified anti-Human CD171, then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.
3. Immunofluorescence staining of Human CD171 in Hela cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-Human CD171 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cells membrane.
应用
ELISA(Det),IHC-P,FCM,ICC/IF
推荐剂量
IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100; FCM: 1:25-1:100; ELISA(Det): 1:1000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CD171 / N-CAML1 / L1CAM (rh CD171 / N-CAML1 / L1CAM; TMPY-01431; NP_000416.1; Met1-Glu1120).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan, and integrins, and it has been revealed that the RGD motif in the sixth Ig domain of L1CAM is a binding site for integrins, thus important for nuclear signaling. Disruption of L1CAM function causes three X-linked neurological syndromes, i.e. hydrocephalus, MASA syndrome (mental retardation, aphasia, shuffling gait, and adducted thumbs), and spastic paraplegia syndrome. Overexpression of L1CAM in normal and cancer cells increased motility, enhanced growth rate, and promoted cell transformation and tumorigenicity. Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression, and a candidate for anti-cancer therapy.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC/HRP/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human CD171 / N-CAML1 / L1CAM protein (TMPY-01431)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

SPG-1SPG 1S-10S 10MIC-5MIC 5HSAS-1HSAS 1CD-171CD 171CAML-1CAML 1

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-L1CAM Antibody (4G234) | purchase Anti-L1CAM Antibody (4G234) | Anti-L1CAM Antibody (4G234) cost | order Anti-L1CAM Antibody (4G234)