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Anti-MNX1/HLXB9 Polyclonal Antibody

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货号 TMAB-08892

Anti-MNX1/HLXB9 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MNX1/HLXB9。Anti-MNX1/HLXB9 Polyclonal Antibody 可用于 WB,ICC/IF,FCM。

Anti-MNX1/HLXB9 Polyclonal Antibody

Anti-MNX1/HLXB9 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08892

Anti-MNX1/HLXB9 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MNX1/HLXB9。Anti-MNX1/HLXB9 Polyclonal Antibody 可用于 WB,ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-MNX1/HLXB9 Polyclonal Antibody is a Rabbit antibody targeting MNX1/HLXB9. Anti-MNX1/HLXB9 Polyclonal Antibody can be used in WB,ICC/IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in lymphoid and pancreatic tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The HB9 homeobox transcription factor regulates gene expression during embryonic development and also in specific adult tissues. HB9 gene mutations are implicated in Curriano syndrome, which is characterized by a triad consisting of a presacral tumor, sacral agenesis and anorectal malformation. In human bone marrow cells, HB9 expression directly correlates with CD34 expression. Furthermore, HB9 expression increases in CD34+ cells that are treated with IL-3 and granulocyte macrophage-colony-stimulating factor. Early in murine development, HB9 is expressed in pancreatic buds (dorsal and ventral) with subsequent expression in differentiating beta cells in the islets of Langerhans. The dorsal lobe of the pancreas fails to form in HB9(-) mice; the resultant pancreas has smaller islets of Langerhans and less beta cells than normal pancreas. The HB9 gene is expressed in the human adult pancreas. In the developing vertebrate embryo, the HB9 gene plays an essential role in motor neuron differentiation. The motor columns of HB9(-) mice are disorganized, lacking phrenic and abducens nerves and exhibiting intercostal nerve defects.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HLXB9
抗原种属
Human
基因名称
MNX1
基因ID
蛋白名称
Motor neuron and pancreas homeobox protein 1
Uniprot ID
功能
Putative transcription factor involved in pancreas development and function.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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