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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Melan A Polyclonal Antibody

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货号 TMAB-08742

Anti-Melan A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Melan A。Anti-Melan A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Melan A Polyclonal Antibody

Anti-Melan A Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08742

Anti-Melan A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Melan A。Anti-Melan A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Melan A Polyclonal Antibody is a Rabbit antibody targeting Melan A. Anti-Melan A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
组织特异性Expression is restricted to melanoma and melanocyte cell lines and retina.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Melan-A
抗原种属
Human
基因名称
MLANA
基因ID
2315
蛋白名称
Melanoma antigen recognized by T-cells 1
Uniprot ID
Q16655
功能
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
化学信息
分子量Theoretical: 13 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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