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Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein

Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein

产品编号 TMPH-02392

Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein is expressed in E. coli expression system. The predicted molecular weight is 63.0 kDa and the accession number is P13699.

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Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein
规格 价格/CNY 货期 数量
20 μg ¥ 3,280 20日内发货
100 μg ¥ 5,300 20日内发货
1 mg ¥ 15,600 20日内发货
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产品目录号及名称: Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein (TMPH-02392)
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产品描述 Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein is expressed in E. coli expression system. The predicted molecular weight is 63.0 kDa and the accession number is P13699.
种属 LASV
表达系统 E. coli
标签 Tag Free
蛋白编号 P13699
氨基酸序列 MSASKEIKSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKSILRVGTLTSDDLLILAADLEKLKSKVIRTERPLSAGVYMGNLSSQQLDQRRALLNMIGMSGGNQGARAGRDGVVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKALGMFISDTPGERNPYENILYKICLSGDGWPYIASRTSITGRAWENTVVDLESDGKPQKADSNNSSKSLQSAGFTAGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTSTPRVVL
蛋白构建 1-569 aa
蛋白纯度 > 85% as determined by SDS-PAGE.
分子量 63.0 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.

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Keywords

recombinant recombinant-proteins proteins protein

 

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