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Anti-CDH23 Polyclonal Antibody

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货号 TMAB-04156

Anti-CDH23 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CDH23。Anti-CDH23 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-CDH23 Polyclonal Antibody

Anti-CDH23 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04156

Anti-CDH23 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CDH23。Anti-CDH23 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-CDH23 Polyclonal Antibody is a Rabbit antibody targeting CDH23. Anti-CDH23 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Particularly strong expression in the retina. Found also in the cochlea.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013].
抗原信息
免疫原
KLH conjugated synthetic peptide: human CDH23
抗原种属
Human
基因名称
CDH23
基因ID
蛋白名称
Cadherin-23
Uniprot ID
功能
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
化学信息
分子量Theoretical: 367 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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