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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ITGAV Polyclonal Antibody 3

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货号 TMAB-07831

Anti-ITGAV Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 ITGAV。Anti-ITGAV Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。

Anti-ITGAV Polyclonal Antibody 3

Anti-ITGAV Polyclonal Antibody 3

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Rating icon 还可以
货号 TMAB-07831

Anti-ITGAV Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 ITGAV。Anti-ITGAV Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

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产品描述
Anti-ITGAV Polyclonal Antibody 3 is a Rabbit antibody targeting ITGAV. Anti-ITGAV Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:500-2000; IHC-Fr: 1:500-2000; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells. ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse Integrin alpha-V light chain
抗原种属
Mouse
基因名称
ITGAV
基因ID
3685
蛋白名称
Integrin alpha-V
功能
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
化学信息
分子量Theoretical: 18/113 kDa. Actual: 24/125 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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