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别名 U2AFBP, U2AF35, U2AF1, U2 snRNP auxiliary factor small subunit, U2 small nuclear RNA auxiliary factor 1, U2 auxiliary factor 35 kDa subunit, Splicing factor U2AF 35 kDa subunit
Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. U2AF1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.9 kDa and the accession number is Q01081.


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Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. U2AF1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.9 kDa and the accession number is Q01081.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 489 | 20日内发货 | |
| 10 μg | ¥ 797 | 20日内发货 | |
| 20 μg | ¥ 1,320 | 20日内发货 | |
| 50 μg | ¥ 1,970 | 20日内发货 | |
| 100 μg | ¥ 2,680 | 20日内发货 | |
| 200 μg | ¥ 4,160 | 20日内发货 | |
| 500 μg | ¥ 7,490 | 20日内发货 | |
| 1 mg | ¥ 11,700 | 20日内发货 |
| 产品描述 | Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. U2AF1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.9 kDa and the accession number is Q01081. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-GST |
| 蛋白编号 | Q01081 |
| 氨基酸序列 | MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF |
| 蛋白构建 | 1-240 aa |
| 蛋白纯度 | > 90% as determined by SDS-PAGE. |
| 缓冲液 | Tris-based buffer, 50% glycerol |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 别名 | U2AFBP, U2AF35, U2AF1, U2 snRNP auxiliary factor small subunit, U2 small nuclear RNA auxiliary factor 1, U2 auxiliary factor 35 kDa subunit, Splicing factor U2AF 35 kDa subunit |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 54.9 kDa (predicted) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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