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别名 p-CDKN1A (Thr145), p-CDKN1A (T145), CDKN1A (p-Thr145), CDKN1A (p-T145)
Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CDKN1A (Thr145)。Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody 可用于 ELISA,IF,IHC-P,WB。
Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CDKN1A (Thr145)。Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody 可用于 ELISA,IF,IHC-P,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,230 | 5日内发货 |
| 产品描述 | Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDKN1A (Thr145). Anti-Phospho-CDKN1A (Thr145) Polyclonal Antibody can be used in ELISA,IF,IHC-P,WB. |
| 别名 | p-CDKN1A (Thr145), p-CDKN1A (T145), CDKN1A (p-Thr145), CDKN1A (p-T145) |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 应用 | ELISAIFIHC-PWB |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 性状 | Liquid |
| 缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 研究背景 | cyclin dependent kinase inhibitor 1A(CDKN1A) Homo sapiens This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lac |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | A synthesized phosphopeptide: human p21 Cip1 around the phosphorylation site of Thr145. AA range:111-160 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 18 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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