Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T68134 | Ro-3201195
化合物Ro-3201195
|
249937-52-8 | 98% |
![]() |
Ro-3201195是一种新型可口服的p38 MAPK 抑制剂,具有很高的选择性。 | ||||
T36010 | P38 MAPK Inhibitor
化合物p38 MAPK抑制剂
|
219138-24-6 | 98% |
![]() |
p38 MAPK Inhibitor 是p38 MAPK 激酶的有效抑制剂(IC50= 35 nM)。p38 MAPK Inhibitor 抑制癌基因RAS 诱导的衰老。 | ||||
T41142 | EM 163
化合物EM 163
|
1206480-93-4 | 98% |
![]() |
EM 163是一种 TIR-TIR 相互作用抑制剂,它是MyD88蛋白的TIR(Toll/白细胞介素-1受体)结构域拟态。EM 163针对IL-1受体中的TIR 结构域,阻断与MyD88的相互作用。EM 163抑制葡萄球菌肠毒素B(SEB)引起的体内炎症细胞因子的产生。EM 163能保护小鼠免受SEB 冲击引起的死亡。在... | ||||
T27627 | Iroxanadine
化合物Iroxanadine
|
203805-20-3 | 98% |
![]() |
Iroxanadine 是一种新型小分子MAPK p38 抑制剂,诱导p38 SAPK 的磷酸化,在用去氧肾上腺素预先收缩的豚鼠肺动脉制剂中诱导浓度依赖性松弛,可用于治疗动脉粥样硬化、糖尿病血管病,微血管心绞痛和外周动脉疾病等血管疾病。 | ||||
T68139 | Scio-323
化合物Scio-323
|
309913-51-7 | 98% |
![]() |
Scio-323是一种可口服的 p38丝裂原活化蛋白(MAPK)激酶抑制剂。 | ||||
T38665 | OVA-E1 peptide TFA
化合物OVA-E1 peptide TFA
|
1262750-80-0 | 98% |
![]() |
OVA-E1 peptide TFA 在突变型和野生型胸腺细胞中都能同样地激活 p38 和 JNK 级联。 | ||||
TN3404 | Altholactone
化合物 TN3404
|
65408-91-5 | 98% |
|
Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of ... | ||||
TN4394 | Kobophenol A
化合物 TN4394
|
124027-58-3 | 98% |
|
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell... | ||||
TN3042 | 4-Hydroxycinnamamide
化合物 TN3042
|
194940-15-3 | 98% |
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases. | ||||
TN4938 | Samidin
化合物 TN4938
|
477-33-8 | 98% |
|
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. | ||||
TN4317 | Isopedicin
化合物 TN4317
|
4431-42-9 | 98% |
|
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr... | ||||
TN5011 | Shizukaol B
化合物 TN5011
|
142279-40-1 | 98% |
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl... | ||||
T7162 | R1487 Hydrochloride
化合物R1487 (Hydrochloride)
|
449808-64-4 | 98% |
![]() |
R1487 Hydrochloride 是一种可口服的高选择性 p38α 抑制剂,对 p38α 和 p38β 的Kd 值分别为 0.2 nM 和 29 nM。 | ||||
T10298 | AMG-548 hydrochloride (864249-60-5 free base)
化合物 T10298
|
T10298 | 98% |
![]() |
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective a... | ||||
TN4774 | Physalin A
化合物 TN4774
|
23027-91-0 | 98% |
![]() |
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc... | ||||
TN1751 | Hydroxycitric acid
2-羟基柠檬酸
|
6205-14-7 | 98% |
![]() |
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to ac... | ||||
TN1347 | 8-Prenylkaempferol
化合物8-Prenylkaempferol
|
28610-31-3 | 98% |
![]() |
8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-in... | ||||
TN4986 | Selinidin
化合物 TN4986
|
19427-82-8 | 98% |
|
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation. | ||||
TN5174 | Trichosanatine
化合物 TN5174
|
169626-16-8 | 98% |
|
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine... | ||||
TMA1743 | Ergosterol peroxide
过氧麦角甾醇
|
2061-64-5 | 98% |
![]() |
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox... |