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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Aspartate Aminotransferase Polyclonal Antibody

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货号 TMAB-02875

Anti-Aspartate Aminotransferase Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Aspartate Aminotransferase。Anti-Aspartate Aminotransferase Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Aspartate Aminotransferase Polyclonal Antibody

Anti-Aspartate Aminotransferase Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02875

Anti-Aspartate Aminotransferase Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Aspartate Aminotransferase。Anti-Aspartate Aminotransferase Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Aspartate Aminotransferase Polyclonal Antibody is a Rabbit antibody targeting Aspartate Aminotransferase. Anti-Aspartate Aminotransferase Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Aspartate Aminotransferase [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate-dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80% of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Aspartate Aminotransferase
抗原种属
Human
基因名称
GOT1
基因ID
2805
蛋白名称
Aspartate aminotransferase, cytoplasmic
Uniprot ID
P17174
功能
Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
化学信息
分子量Theoretical: 46 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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