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Anti-CEACAM3 Antibody-PE (7Z451)

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Anti-CEACAM3 Antibody-PE (7Z451)
产品编号 TMAY-02152P
别名 W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3

Anti-CEACAM3 Antibody-PE (7Z451) 是一种 PE-conjugated Mouse 抗体,靶向 CEACAM3。Anti-CEACAM3 Antibody-PE (7Z451) 可用于 FCM。

Anti-CEACAM3 Antibody-PE (7Z451)

Anti-CEACAM3 Antibody-PE (7Z451)

Rating icon 还可以
Anti-CEACAM3 Antibody-PE (7Z451)
产品编号 TMAY-02152P 别名 W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3

Anti-CEACAM3 Antibody-PE (7Z451) 是一种 PE-conjugated Mouse 抗体,靶向 CEACAM3。Anti-CEACAM3 Antibody-PE (7Z451) 可用于 FCM。

规格价格库存数量
25 T
¥ 1,080
5日内发货
100 T
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-CEACAM3 Antibody-PE (7Z451) is a PE-conjugated Mouse antibody targeting CEACAM3. Anti-CEACAM3 Antibody-PE (7Z451) can be used in FCM.
别名W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3
Ig Type
Mouse IgG1
克隆号
7Z451
交叉反应
Human
验证活性
Flow cytometric analysis of anti-human CEACAM3 (CD66d) on human whole blood granulocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable granulocytes.
应用
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM3 / CD66d (rh CEACAM3 / CD66d; TMPY-01850; NP_001806.2; Met 1-Gly 155) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. Monoclonal antibodies grouped in the CD66 cluster recognize CEACAM members. Ectopic CD66 expression is commonly detected in B-cell lineage acute lymphoblastic leukemia (ALL). CEACAM3 mediates phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3. CEACAM3 is characterized by rapid stimulation of the GTPase Rac.
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Human CEACAM3 / CD66d protein (TMPY-01850)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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