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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CDCA2 Polyclonal Antibody

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货号 TMAB-04140

Anti-CDCA2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CDCA2。Anti-CDCA2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CDCA2 Polyclonal Antibody

Anti-CDCA2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04140

Anti-CDCA2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CDCA2。Anti-CDCA2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-CDCA2 Polyclonal Antibody is a Rabbit antibody targeting CDCA2. Anti-CDCA2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Note=Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin. [ALTERNATIVE PRODUCTS] Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q69YH5-1; Sequence=Displayed; Name=2; IsoId=Q69YH5-2; Sequence=VSP_025598, VSP_025599; Note=No experimental confirmation available.
组织特异性Ubiquitously expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CDCA2 is a regulator of chromosome structure during mitosis. CDCA2 forms an essential complex with protein phosphatase PP1-gamma subunit 1 (PPP1CC) and is required for the recruitment of PP1 to chromatin. Knockdown of CDCA2 by RNAi causes large-scale cell death by apoptosis, as does overexpression of a dominant-negative mutant of the protein.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CDCA2
抗原种属
Human
基因名称
CDCA2
基因ID
157313
蛋白名称
Cell division cycle-associated protein 2
Uniprot ID
Q69YH5
功能
Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
化学信息
分子量Theoretical: 113 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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