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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DKK2 Polyclonal Antibody

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货号 TMAB-00549

别名 hDkk-2, Dkk-2, DKK2, Dickkopf-related protein 2, Dickkopf-2

Anti-DKK2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DKK2。Anti-DKK2 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB。

Anti-DKK2 Polyclonal Antibody

Anti-DKK2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00549 别名 hDkk-2, Dkk-2, DKK2, Dickkopf-related protein 2, Dickkopf-2

Anti-DKK2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DKK2。Anti-DKK2 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-DKK2 Polyclonal Antibody is a Rabbit antibody targeting DKK2. Anti-DKK2 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB.
别名hDkk-2, Dkk-2, DKK2, Dickkopf-related protein 2, Dickkopf-2
Ig Type
IgG
反应种属
(predicted:Human,Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit,Sheep)
应用ELISAICC/IFIFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Expressed in heart, brain, skeletal muscle and lung.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human DKK2
抗原种属
Human
基因名称
DKK2
基因ID
27123
蛋白名称
Dickkopf-related protein 2
Uniprot ID
Q9UBU2
研究领域
Secreted
功能
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器

关键词

hDkk2DKK 2Dickkopf2
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