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Anti-WSTF Antibody (7C137) 是一种 Rabbit 抗体,靶向 WSTF。Anti-WSTF Antibody (7C137) 可用于 WB,FCM。
Anti-WSTF Antibody (7C137) 是一种 Rabbit 抗体,靶向 WSTF。Anti-WSTF Antibody (7C137) 可用于 WB,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-WSTF Antibody (7C137) is a Rabbit antibody targeting WSTF. Anti-WSTF Antibody (7C137) can be used in WB,FCM. |
别名 | WSTF, Williams-Beuren syndrome chromosomal region 9 protein, Williams-Beuren syndrome chromosomal region 10 protein, Williams syndrome transcription factor, Williams Beuren syndrome chromosome region 9 protein, WBSCR9, WBSCR10, WBSC-10, WBSC10, WBSC 10, WBRS-9, WBRS9, WBRS 9, WALP-2, WALP2, Tyrosine-protein kinase BAZ1B, transcription factor WSTF, hWALP-2, hWALP2, hWALP 2, Bromodomain adjacent to zinc finger domain protein 1B, BAZ1B_HUMAN, baz1b |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of WSTF on SiHa cell lysates using anti-WSTF at 1/500 dilution. 2. Flow cytometric analysis of K562 cells with WSTF antibody at 1/50 dilution (Fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; Yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
应用 | |
推荐剂量 | WB: 1:500-1000; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication. |
偶联 | Unconjugated |
Uniprot ID |
分子量 | Theoretical: 171 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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