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酶联受体 (Enzyme-Linked Receptors)

酶联受体是一种跨膜受体,其中细胞外配体的结合引起细胞内酶活性。因此,酶联受体是一种具有催化和受体功能的完整膜蛋白。大多数酶联受体是酪氨酸激酶受体。酶联受体有两个重要的结构域:细胞外配体结合结构域、细胞内结构域,具有催化功能和单个跨膜螺旋。信号分子与细胞外部的受体结合,并引起位于细胞内受体催化功能的构象变化。

HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
TMPY-01137
HER2 ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
  • ¥ 3260
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c-Kit Protein, Human, Recombinant (hFc)
TMPY-04051
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
  • ¥ 2520
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p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)
TMPY-04429
p38 gamma MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
  • ¥ 3170
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MERTK/Mer Protein, Mouse, Recombinant (His)
TMPK-01022
MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. MERTK Mer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.38 kDa and the accession number is Q60805.
  • ¥ 2660
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EphA2 Protein, Human, Recombinant (His)
TMPY-03552
EphA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P29317.
  • ¥ 3820
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EphA2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06812
EphA2 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 60 kDa and the accession number is NP_034269.2.
  • ¥ 3820
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TrkC Protein, Human, Recombinant (His)
TMPY-00945
TrkC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.1 kDa and the accession number is Q16288-2.
  • ¥ 3820
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ROR1 Protein, Human, Recombinant, Biotinylated
TMPY-04986
ROR1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 42.8 kDa and the accession number is Q01973.
  • ¥ 2440
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TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
  • ¥ 3980
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HER3/ERBB3 Protein, Human, Recombinant (His)
TMPY-01389
HER3 ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
  • ¥ 1470
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HER2/ERBB2 Protein, Human, Recombinant (His)
TMPJ-00778
HER2 ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
  • ¥ 740
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FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00395
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
  • ¥ 5180
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HER2/ERBB2 Protein, Human, Recombinant
TMPY-00167
HER2 ERBB2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 70 kDa and the accession number is P04626-1.
  • ¥ 4990
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TrkA Protein, Human, Recombinant (His)
TMPY-01084
TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04629-1.
  • ¥ 2900
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TrkB Protein, Human, Recombinant (His)
TMPY-00751
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
  • ¥ 2260
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TGFBR2 Protein, Human, Recombinant (His)
TMPY-05157
TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
  • ¥ 3170
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TIE2 Protein, Human, Recombinant (His)
TMPY-01064
TIE2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82 kDa and the accession number is AAA61139.1.
  • ¥ 2520
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AXL Protein, Human, Recombinant (His)
TMPY-01601
AXL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAB20305.1.
  • ¥ 1350
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ACVR2A Protein, Human, Recombinant (hFc & His)
TMPJ-00315
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
  • ¥ 380
5日内发货
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FGFR4 Protein, Human, Recombinant (His & Avi)
TMPK-00379
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
  • ¥ 1470
5日内发货
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HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
TMPK-00499
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. HGFR c-Met Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 32.5 kDa (α chain) and 69.9 kDa (β chain) and the accession number is A0A2K5UM36.
  • ¥ 3100
5日内发货
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MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
TMPJ-01143
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER AXL TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. It can't be expressed in normal B- and T-lymphocytes, but it is usually expressed in numerous neoplastic B- and T-cell lines. MERTK could regulate many physiological processes, such as cell survival, migration, differentiation. It was demonstrated that the MERTK plays critical role in the engulfment and efficient clearance of apoptotic cells, platelet aggregation, and cytoskeleton reorganization. Not only these, it also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. In addition, MERTK could regulate rod outer segments fragments phagocytosis in the retinal pigment epithelium (RPE), deficiency in MERTK are the cause of retinitis pigmentosa.
  • ¥ 1170
5日内发货
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TIE2 Protein, Human, Recombinant (hFc)
TMPJ-00642
TIE2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession number is Q02763-1.
  • ¥ 380
5日内发货
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FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
TMPJ-00391
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
  • ¥ 550
5日内发货
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FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
TMPK-00398
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
  • ¥ 3400
5日内发货
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TIE2 Protein, Mouse, Recombinant (His)
TMPY-07215
TIE2 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q02858.
  • ¥ 3820
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HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)
TMPY-00636
HER2 ERBB2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.8 kDa and the accession number is G7PUM4.
  • ¥ 3820
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FLT1 Protein, Human, Recombinant (hFc)
TMPY-00119
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
  • ¥ 2530
5日内发货
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HER2/ERBB2 Protein, Human, Recombinant (His), PE-Labeled
TMPY-06994
HER2 ERBB2 Protein, Human, Recombinant (His), PE-Labeled is expressed in HEK293 Cells. The accession number is P04626.
  • ¥ 2930
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BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
TMPY-00614
BMPR1A ALK-3 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is A0A8C0S7K5.
  • ¥ 2530
5日内发货
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EphA2 Protein, Mouse, Recombinant (His)
TMPY-01777
EphA2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58 kDa and the accession number is Q03145.
  • ¥ 3820
5日内发货
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EphB2 Protein, Human, Recombinant (His & hFc)
TMPY-00784
EphB2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 86 kDa and the accession number is P29323-2.
  • ¥ 3820
5日内发货
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ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
TMPY-00658
ALK-2 ACVR1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is D3DPA4.
  • ¥ 5750
5日内发货
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HER3/ERBB3 Protein, Human, Recombinant (hFc)
TMPY-00795
HER3 ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1.
  • ¥ 1930
5日内发货
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PDGFRA Protein, Human, Recombinant (His)
TMPY-01139
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
  • ¥ 3820
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FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00847
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the accession number is P21803-2.
  • ¥ 3100
5日内发货
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PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00420
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59.2 kDa and the accession number is P16234.
  • ¥ 5180
5日内发货
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HGFR/c-Met Protein, Canine, Recombinant (His)
TMPY-02068
HGFR c-Met Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103 kDa and the accession number is Q75ZY9.
  • ¥ 3820
5日内发货
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HER3/ERBB3 Protein, Rhesus, Recombinant (hFc)
TMPY-02478
HER3 ERBB3 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.7 kDa and the accession number is XP_001113953.2.
  • ¥ 3820
5日内发货
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BMPRIB Protein, Human, Recombinant (hFc)
TMPY-03362
BMPRIB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.7 kDa and the accession number is O00238-1.
  • ¥ 5750
5日内发货
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FGFR2 Protein, Mouse, Recombinant (His)
TMPY-03389
FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is AAA39377.1.
  • ¥ 3820
5日内发货
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DDR1 Protein, Rat, Recombinant (hFc)
TMPY-03541
DDR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.9 kDa and the accession number is Q6MG19.
  • ¥ 3820
5日内发货
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TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST)
TMPY-04575
TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.2kDa and the accession number is Q02858.
  • ¥ 2530
5日内发货
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ALK-4/ACVR1B Protein, Human, Recombinant (His)
TMPY-01293
ALK-4 ACVR1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13 kDa and the accession number is P36896-1.
  • ¥ 3820
5日内发货
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HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST)
TMPY-04379
HGFR c-Met Protein, Human, Recombinant (aa 956-1390, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.8 kDa and the accession number is P08581-1.
  • ¥ 3170
5日内发货
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EphA4 Protein, Human, Recombinant (aa 570-986, His & GST)
TMPY-04485
EphA4 Protein, Human, Recombinant (aa 570-986, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is P54764.
  • ¥ 3170
5日内发货
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ALK-1 Protein, Cynomolgus, Recombinant (His)
TMPY-00310
ALK-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is A0A2K5WXU2.
  • ¥ 3820
5日内发货
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TIE2 Protein, Rhesus, Recombinant (His)
TMPY-05049
TIE2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is G7NFP9.
  • ¥ 3820
5日内发货
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