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酶联受体 (Enzyme-Linked Receptors)

酶联受体是一种跨膜受体,其中细胞外配体的结合引起细胞内酶活性。因此,酶联受体是一种具有催化和受体功能的完整膜蛋白。大多数酶联受体是酪氨酸激酶受体。酶联受体有两个重要的结构域:细胞外配体结合结构域、细胞内结构域,具有催化功能和单个跨膜螺旋。信号分子与细胞外部的受体结合,并引起位于细胞内受体催化功能的构象变化。

HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
TMPY-01137
HER2 ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
  • ¥ 3260
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c-Kit Protein, Human, Recombinant (hFc)
TMPY-04051
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
  • ¥ 2520
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p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)
TMPY-04429
p38 gamma MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
  • ¥ 3170
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MERTK/Mer Protein, Mouse, Recombinant (His)
TMPK-01022
MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. MERTK Mer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.38 kDa and the accession number is Q60805.
  • ¥ 2660
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EphA2 Protein, Human, Recombinant (His)
TMPY-03552
EphA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P29317.
  • ¥ 3820
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EphA2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06812
EphA2 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 60 kDa and the accession number is NP_034269.2.
  • ¥ 3820
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ROR1 Protein, Human, Recombinant, Biotinylated
TMPY-04986
ROR1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 42.8 kDa and the accession number is Q01973.
  • ¥ 2440
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TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
  • ¥ 3980
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HER3/ERBB3 Protein, Human, Recombinant (His)
TMPY-01389
HER3 ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
  • ¥ 1470
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HER2/ERBB2 Protein, Human, Recombinant (His)
TMPJ-00778
HER2 ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
  • ¥ 740
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FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00395
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
  • ¥ 5180
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TrkC Protein, Human, Recombinant (His)
TMPY-00945
TrkC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.1 kDa and the accession number is Q16288-2.
  • ¥ 3820
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HER2/ERBB2 Protein, Human, Recombinant
TMPY-00167
HER2 ERBB2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 70 kDa and the accession number is P04626-1.
  • ¥ 4990
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TrkA Protein, Human, Recombinant (His)
TMPY-01084
TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04629-1.
  • ¥ 2900
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TrkB Protein, Human, Recombinant (His)
TMPY-00751
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
  • ¥ 2260
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TGFBR2 Protein, Human, Recombinant (His)
TMPY-05157
TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
  • ¥ 3170
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TIE2 Protein, Human, Recombinant (His)
TMPY-01064
TIE2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82 kDa and the accession number is AAA61139.1.
  • ¥ 2520
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AXL Protein, Human, Recombinant (His)
TMPY-01601
AXL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAB20305.1.
  • ¥ 1350
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TIE2 Protein, Mouse, Recombinant (His)
TMPY-07215
TIE2 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q02858.
  • ¥ 3820
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DDR1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-07033
DDR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is NP_001189452.2.
  • ¥ 3820
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TIE2 Protein, Human, Recombinant (hFc)
TMPJ-00642
TIE2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession number is Q02763-1.
  • ¥ 380
5日内发货
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TGFBR1 Protein, Mouse, Recombinant (hFc)
TMPJ-01178
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Phosphorylated TGF-beta RI can then transiently bind and phosphorylate Smad2 and Smad3. TGF-beta functions as a tumor suppressor by inhibiting the cell cycle in the G1 phase. Administration of TGF-beta is able to protect against mammary tumor development in transgenic mouse models in vivo. Disruption of the TGF-beta SMAD pathway has been implicated in a variety of human cancers, with the majority of colon and gastric cancers being caused by an inactivating mutation of TGF-beta RII. TGF-beta RI is likely important during development, since mice deficient for TGF-beta RI die at midgestation with severe defects in vascular development of the yolk sac and placenta, and an absence of circulating red blood cells. Furthermore, TGF-beta RI appears to be involved in proper lymphatic network development.
  • ¥ 890
5日内发货
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ROR2 Protein, Human, Recombinant (hFc)
TMPK-00579
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. ROR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 68 kDa and the accession number is A1L4F5.
  • ¥ 3100
5日内发货
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FGFR4 Protein, Human, Recombinant (His & Avi)
TMPK-00379
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
  • ¥ 1470
5日内发货
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MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
TMPJ-01143
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER AXL TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. It can't be expressed in normal B- and T-lymphocytes, but it is usually expressed in numerous neoplastic B- and T-cell lines. MERTK could regulate many physiological processes, such as cell survival, migration, differentiation. It was demonstrated that the MERTK plays critical role in the engulfment and efficient clearance of apoptotic cells, platelet aggregation, and cytoskeleton reorganization. Not only these, it also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. In addition, MERTK could regulate rod outer segments fragments phagocytosis in the retinal pigment epithelium (RPE), deficiency in MERTK are the cause of retinitis pigmentosa.
  • ¥ 1170
5日内发货
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PDGF R beta/CD140b Protein, Canine, Recombinant (His)
TMPK-01050
PDGF R beta CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
  • ¥ 3100
5日内发货
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FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00391
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.
  • ¥ 5180
5日内发货
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HER4/ERBB4 Protein, Human, Recombinant (His & Avi)
TMPK-00448
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS. HER4 ERBB4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 72.7 kDa and the accession number is Q15303-1.
  • ¥ 2210
5日内发货
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FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00847
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the accession number is P21803-2.
  • ¥ 3100
5日内发货
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FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00401
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
  • ¥ 5180
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PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
TMPK-00943
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.32 kDa and the accession number is Q0PW86.
  • ¥ 3100
5日内发货
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FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00380
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1.
  • ¥ 5180
5日内发货
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HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
TMPK-00453
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3 ERBB3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.
  • ¥ 1770
5日内发货
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PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00420
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59.2 kDa and the accession number is P16234.
  • ¥ 5180
5日内发货
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HER3/ERBB3 Protein, Human, Recombinant (hFc)
TMPY-00795
HER3 ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1.
  • ¥ 1930
5日内发货
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HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05753
HER3 ERBB3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1.
  • ¥ 1950
5日内发货
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p38 gamma/MAPK12 Protein, Human, Recombinant
TMPY-04430
p38 gamma MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
  • ¥ 3170
5日内发货
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ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05603
ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.2 kDa and the accession number is Q01973.
  • ¥ 2940
5日内发货
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HGFR/c-Met Protein, Canine, Recombinant (His)
TMPY-02068
HGFR c-Met Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103 kDa and the accession number is Q75ZY9.
  • ¥ 3820
5日内发货
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BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
TMPY-00614
BMPR1A ALK-3 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is A0A8C0S7K5.
  • ¥ 2530
5日内发货
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BMPRIB Protein, Human, Recombinant (hFc)
TMPY-03362
BMPRIB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.7 kDa and the accession number is O00238-1.
  • ¥ 5750
5日内发货
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HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)
TMPY-00636
HER2 ERBB2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.8 kDa and the accession number is G7PUM4.
  • ¥ 3820
现货
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TIE2 Protein, Rhesus, Recombinant (His)
TMPY-05049
TIE2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is G7NFP9.
  • ¥ 3820
5日内发货
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EphA2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05588
EphA2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 59.4 kDa and the accession number is A0A024QZA8.
  • ¥ 2360
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FGFR4 Protein, Human, Recombinant (hFc)
TMPY-00806
FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is P22455-1.
  • ¥ 3820
5日内发货
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TIE2 Protein, Human, Recombinant (His & hFc)
TMPY-00930
TIE2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 108.5 kDa and the accession number is AAA61139.1.
  • ¥ 3820
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FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00384
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
  • ¥ 2210
5日内发货
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HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
TMPK-00452
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3 ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.
  • ¥ 5930
5日内发货
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