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Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-KRT8 (Ser74)。Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody 可用于 WB,IF。
Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-KRT8 (Ser74)。Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody 可用于 WB,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KRT8 (Ser74). Anti-Phospho-KRT8 (Ser74) Polyclonal Antibody can be used in WB,IF. |
别名 | p-KRT8 (Ser74), p-KRT8 (S74), KRT8 (p-Ser74), KRT8 (p-S74) |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of extracts from HepG2 cells untreated or treated with EGF using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308. 2. Immunofluorescence staining of methanol-fixed Hela cells using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308. 3. Western blot analysis of extracts from 293 cells, treated with calf intestinal phosphatase (CIP), using Keratin 8 (Phospho-Ser74) Antibody TMAC-02308. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8) |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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