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顶部生物活性储存和溶解信息计算器

Anti-DDOST Antibody (5B994)

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Anti-DDOST Antibody (5B994)
产品编号 TMAY-02356
别名 WBP1, OST48, OST, OKSWcl45, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic), CDG1R, AGER1

Anti-DDOST Antibody (5B994) 是一种 Mouse 抗体，靶向 DDOST。Anti-DDOST Antibody (5B994) 可用于 ELISA。

Anti-DDOST Antibody (5B994)
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Anti-DDOST Antibody (5B994)

Rating icon 还可以
Anti-DDOST Antibody (5B994)
产品编号 TMAY-02356 别名 WBP1, OST48, OST, OKSWcl45, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic), CDG1R, AGER1

Anti-DDOST Antibody (5B994) 是一种 Mouse 抗体，靶向 DDOST。Anti-DDOST Antibody (5B994) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,689
5日内发货
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产品介绍

生物活性
产品描述
Anti-DDOST Antibody (5B994) is a Mouse antibody targeting DDOST. Anti-DDOST Antibody (5B994) can be used in ELISA.
别名WBP1, OST48, OST, OKSWcl45, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic), CDG1R, AGER1
Ig Type
Mouse IgG2a
克隆号
5B994
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DDOST / OST48 (rh DDOST / OST48; TMPY-02050; P39656-1; Ser43-Pro427). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The enzyme oligosaccharyltransferase (dolichyl-diphosphooligosaccharide-protein glycosyltransferase) (DDOST), or 48-kDa subunit (OST48) is one of the catalytic subunits in this complex, exerts a typical type I membrane topology, containing a large luminal domain, a hydrophobic transmembrane domain and a short cytosolic peptide tail. DDOST/OST48 catalyzes the transfer of a high-mannose oligosaccharide (GlcNac2Man9Glc3) from a dolichol-linked oligosaccharide donor (dolichol-P-GlcNac2Man9Glc3) onto the asparagine acceptor site within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains across the membrane of the endoplasmic reticulum. The mammalian oligosaccharyltransferase (OST) is an oligomeric complex composed of three type I transmembrane proteins of the endoplasmic reticulum: ribophorin I (RI), ribophorin II (RII), and OST48. OST48 is not a glycoprotein and is not recognized by antibodies to either ribophorin. Like ribophorins I and II, OST48 was found to be an integral membrane protein, with the majority of the polypeptide located within the lumen of the endoplasmic reticulum (ER). OST48 does not show significant amino acid sequence homology to either ribophorin I or II. It had been found that only the luminal domain of RI contains ER retention information. The dilysine motif in OST48 functions as an ER localization motif because OST48 in which the two lysine residues are replaced by serine (OST48ss) is no longer retained in the ER and is found instead also at the plasma membrane.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human DDOST / OST48 protein (TMPY-02050)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

WBP-1WBP 1OST-48OST 48non-catalyticAGER-1AGER 1

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5.0
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