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Anti-IL-10 Antibody (9H714)
还可以产品编号 TMAH-00607
别名 白细胞介素, TGIF, MGC126451, MGC126450, Interleukin-10, IL10A, IL-10, GVHDS, CSIF, B-TCGF
Anti-IL-10 Antibody (9H714) 是一种抗体，靶向 IL-10。Anti-IL-10 Antibody (9H714) 可用于 ELISA, IHC。
Anti-IL-10 Antibody (9H714)
Anti-IL-10 Antibody (9H714)
还可以产品编号 TMAH-00607 别名 白细胞介素, TGIF, MGC126451, MGC126450, Interleukin-10, IL10A, IL-10, GVHDS, CSIF, B-TCGF
Anti-IL-10 Antibody (9H714) 是一种抗体，靶向 IL-10。Anti-IL-10 Antibody (9H714) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-10 Antibody (9H714) is an antibody targeting IL-10. Anti-IL-10 Antibody (9H714) can be used in ELISA, IHC. |
| 别名 | 白细胞介素, TGIF, MGC126451, MGC126450, Interleukin-10, IL10A, IL-10, GVHDS, CSIF, B-TCGF |
| Ig Type | hIgG1 |
| 克隆号 | 9H714 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00607 diluted at 1:300 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Human IgG labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha. Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation. In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human IL10 Protein |
| 抗原种属 | Human |
| 基因ID | 3586 |
| Uniprot ID | |
| 研究领域 | Cancer, Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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