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Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395)
还可以产品编号 TMAY-02705
Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) 是一种 Mouse 抗体，靶向 UMP-CMP kinase/CMPK1。Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) 可用于 ELISA,ICC/IF。
Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395)
Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395)
还可以产品编号 TMAY-02705
Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) 是一种 Mouse 抗体，靶向 UMP-CMP kinase/CMPK1。Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) 可用于 ELISA,ICC/IF。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) can be used in ELISA,ICC/IF. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3Z395 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of Human CMPK1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human CMPK1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green). Positive staining was localized to nucleus and cytoplasm. |
| 应用 | ELISA,ICC/IF |
| 推荐剂量 | ELISA: 1:1000-1:2000; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CMPK1 (rh CMPK1; TMPY-04480; P30085; Met1-Gly196). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CMPK1 protein (TMPY-04480) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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