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Anti-CALML5 Antibody (8Y568) 是一种 Mouse 抗体,靶向 CALML5。Anti-CALML5 Antibody (8Y568) 可用于 ELISA(Cap)。
Anti-CALML5 Antibody (8Y568) 是一种 Mouse 抗体,靶向 CALML5。Anti-CALML5 Antibody (8Y568) 可用于 ELISA(Cap)。
产品描述 | Anti-CALML5 Antibody (8Y568) is a Mouse antibody targeting CALML5. Anti-CALML5 Antibody (8Y568) can be used in ELISA(Cap). |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 8Y568 |
交叉反应 | Human |
应用 | ELISA(Cap) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CALML5 (rh CALML5; TMPY-01953; AAH39172.1; Met1-Glu146). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CALML5 Protein (TMPY-01953) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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