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Anti-IFNLR1 Antibody (9X278)
还可以产品编号 TMAH-00597
Anti-IFNLR1 Antibody (9X278) 是一种 Mouse 抗体，靶向 IFNLR1。Anti-IFNLR1 Antibody (9X278) 可用于 ELISA, IF。
Anti-IFNLR1 Antibody (9X278)
Anti-IFNLR1 Antibody (9X278)
还可以产品编号 TMAH-00597
Anti-IFNLR1 Antibody (9X278) 是一种 Mouse 抗体，靶向 IFNLR1。Anti-IFNLR1 Antibody (9X278) 可用于 ELISA, IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IFNLR1 Antibody (9X278) is a Mouse antibody targeting IFNLR1. Anti-IFNLR1 Antibody (9X278) can be used in ELISA, IF. |
| Ig Type | IgG2a |
| 克隆号 | 9X278 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunofluorescence staining of Hela cells with（TMAH-00597）at 1:90, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). 2. Immunofluorescence staining of U251 cells with（TMAH-00597）at 1:90, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). |
| 应用 | ELISA, IF |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 纯度 | >95% |
| 研究背景 | The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: IFNLR1 Protein (21-228AA) |
| 抗原种属 | Human |
| 基因ID | 163702 |
| Uniprot ID | |
| 研究领域 | Signal Transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
关键词
Likely interleukin or cytokine receptor 2 (LICR2)LICR2LICR 2Interleukin-28 receptor subunit α (IL-28 receptor subunit α;IL-28R-α;IL-28RA)Interleukin-28 receptor subunit alpha (IL-28 receptor subunit alpha;IL-28R-alpha;IL-28RA)Interleukin-28 receptor subunit a (IL-28 receptor subunit a;IL-28R-a;IL-28RA)Interferon λ receptor 1Interferon lambda receptor 1IL-28RAIL28RAIFN-λ-R1IFN-λ receptor 1IFN-λ R1IFNλ R1IFNLR1IFNLR 1IFN-lambda-R1IFN-lambda receptor 1IFN-lambda R1Cytokine receptor family 2 member 12 (CRF2-12)Cytokine receptor class-II member 12CRF2-12CRF212
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