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Anti-Sox3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Sox3。Anti-Sox3 Polyclonal Antibody 可用于 WB。
Anti-Sox3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Sox3。Anti-Sox3 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Sox3 Polyclonal Antibody is a Rabbit antibody targeting Sox3. Anti-Sox3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Chicken,Sheep,Cow) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nuclear. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-3, also known as MRGH or SOXB, is implicated in mental retardation X-linked with isolated growth hormone deficiency (MRXGH) and infundibular hypoplasia and hypopituitarism. |
| 免疫原 | KLH conjugated synthetic peptide: human Sox3 |
| 抗原种属 | Human |
| 基因名称 | SOX3 |
| 基因ID | |
| 蛋白名称 | Transcription factor SOX-3 |
| Uniprot ID | |
| 功能 | SOX 3 is also known as SRY related HMG BOX gene 3. All SOX proteins have a single HMG box. Humans with mutations in SOX3 have panhypopituitarism. Conditional disruption of SOX3 in mice demonstrates that anterior pituitary development depends on SOX3 expression in the overlying neural ectoderm. |
| 分子量 | Theoretical: 45 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |