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顶部生物活性储存和溶解信息计算器

Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody

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Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody
产品编号 TMAC-01439
别名 p-FANCD2 (Ser222), p-FANCD2 (S222), FANCD2 (p-Ser222), FANCD2 (p-S222)

Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-FANCD2 (Ser222)。Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody 可用于 WB。

Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody

Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody
产品编号 TMAC-01439 别名 p-FANCD2 (Ser222), p-FANCD2 (S222), FANCD2 (p-Ser222), FANCD2 (p-S222)

Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-FANCD2 (Ser222)。Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,490
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100 μL
¥ 2,235
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FANCD2 (Ser222). Anti-Phospho-FANCD2 (Ser222) Polyclonal Antibody can be used in WB.
别名p-FANCD2 (Ser222), p-FANCD2 (S222), FANCD2 (p-Ser222), FANCD2 (p-S222)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extracts from HT29 cells treated with CalyculinA using Phospho-FANCD2 (Ser222) antibody TMAC-01439. The lane on the right is treated with the antigen-specific peptide.
应用
WB
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 222 (G-D-S(p)-Q-H) derived from Human FANCD2
抗原种属
human
Uniprot ID
Q9BXW9
化学信息
分子量Actual: 166 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pFANCD2 (Ser222)pFANCD2 (S222)FANCD2 (pSer222)FANCD2 (pS222)FANCD2 (phospho-Ser222)FANCD2 (phospho-S222)

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4个月前
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