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Anti-Integrin alpha 4 Antibody (6M673) 是一种 Rabbit 抗体,靶向 Integrin alpha 4。Anti-Integrin alpha 4 Antibody (6M673) 可用于 WB,IHC,FCM。
Anti-Integrin alpha 4 Antibody (6M673) 是一种 Rabbit 抗体,靶向 Integrin alpha 4。Anti-Integrin alpha 4 Antibody (6M673) 可用于 WB,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-Integrin alpha 4 Antibody (6M673) is a Rabbit antibody targeting Integrin alpha 4. Anti-Integrin alpha 4 Antibody (6M673) can be used in WB,IHC,FCM. |
别名 | VLA-4 subunit alpha, VLA4, VLA 4 subunit alpha, Very late activation protein 4 receptor, OTTHUMP00000205320, MGC90518, ITGA4, ITA4_HUMAN, Integrin α4, Integrin α 4, Integrin alpha-IV, Integrin alpha-4, Integrin alpha4, Integrin alpha IV, Integrin alpha 4 subunit, Integrin alpha 4, Integrin a4, Integrin a 4, Integrin, IA4, CD49d, CD49 antigen-like family member D, CD49 antigen like family member D, Antigen CD49D, alpha 4 subunit of VLA 4 receptor), alpha 4 subunit of VLA 4 receptor, alpha 4 subunit, alpha 4 (antigen CD49D, 269C wild type |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Integrin alpha 4 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Integrin alpha 4 antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of Jurkat cells with Integrin alpha 4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti mouse IgG was used as the secondary antibody. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; FCM: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
分子量 | Theoretical: 150 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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