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ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

产品编号 TMPJ-00850
别名: Protein T1, suppression of tumorigenicity 2, Ly84, DER4, Fit-1, Lymphocyte antigen 84, Interleukin-1 receptor-like 1, IL-1 R4, ST2V, ST2L, IL-33R, Protein ST2, Il1rl1, IL-1RL1

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.

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ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
规格 价格/CNY 货期 数量
10 μg ¥ 740 现货
50 μg ¥ 1,970 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) (TMPJ-00850)
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生物活性
技术参数
产品性质
生物活性 Immobilized Mouse ST2-His at 5μg/ml (100 μl/well) can bind Rhesus Macaque IL-33-His. The ED50 of Rhesus Macaque IL-33-His is 82.03 ng/ml. (Regularly tested)

TargetMol Bioactive

产品描述 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
种属 Mouse
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 P14719-2
别名 Protein T1, suppression of tumorigenicity 2, Ly84, DER4, Fit-1, Lymphocyte antigen 84, Interleukin-1 receptor-like 1, IL-1 R4, ST2V, ST2L, IL-33R, Protein ST2, Il1rl1, IL-1RL1
氨基酸序列 Ser27-Ala337
蛋白构建 Ser27-Ala337
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

TargetMol

分子量 55-70 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.

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Keywords

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Protein T1 suppression of tumorigenicity 2 Ly84 DER4 Fit-1 Lymphocyte antigen 84 Interleukin-1 receptor-like 1 IL-1 R4 ST2V ST2L IL-33R Protein ST2 Il1rl1 DER-4 IL-1RL1 DER 4 recombinant recombinant-proteins proteins protein

 

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