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Anti-ESAM Antibody (4I805)

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产品编号 TMAY-00425
别名 endothelial cell adhesion molecule

Anti-ESAM Antibody (4I805) 是一种 Rabbit 抗体,靶向 ESAM。Anti-ESAM Antibody (4I805) 可用于 ELISA。

Anti-ESAM Antibody (4I805)

Anti-ESAM Antibody (4I805)

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产品编号 TMAY-00425 别名 endothelial cell adhesion molecule

Anti-ESAM Antibody (4I805) 是一种 Rabbit 抗体,靶向 ESAM。Anti-ESAM Antibody (4I805) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-ESAM Antibody (4I805) is a Rabbit antibody targeting ESAM. Anti-ESAM Antibody (4I805) can be used in ELISA.
别名endothelial cell adhesion molecule
Ig Type
Monoclonal Rabbit IgG
克隆号
4I805
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ESAM (rh ESAM; TMPY-01312; NP_620411.2; Met 1-Ala 248).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human ESAM protein (TMPY-01312)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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