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Anti-CD131 Antibody (2H127) 是一种 Mouse 抗体,靶向 CD131。Anti-CD131 Antibody (2H127) 可用于 ELISA。
Anti-CD131 Antibody (2H127) 是一种 Mouse 抗体,靶向 CD131。Anti-CD131 Antibody (2H127) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 1,684 | 5日内发货 |
产品描述 | Anti-CD131 Antibody (2H127) is a Mouse antibody targeting CD131. Anti-CD131 Antibody (2H127) can be used in ELISA. |
别名 | colony stimulating factor 2 receptor, β, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
Ig Type | Monoclonal Mouse IgG2a |
克隆号 | 2H127 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD131 / CSF2RB / IL3RB / IL5RB (rh CD131 / CSF2RB / IL3RB / IL5RB; TMPY-01650; NP_000386.1; Met 1-Trp 443). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (IL3RB), is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this protein have been reported to be associated with protein alveolar proteinosis (PAP). CD131 belongs to the type I cytokine receptor family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Defects in CD131/CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5). SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CSF2RB protein (TMPY-01650) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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