Anti-PTS Antibody (6H822)

Name: Anti-PTS Antibody (6H822)
Brand: TargetMol
SKU: TMAY-02720
Rating: 4.5 (1 reviews)

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产品编号 TMAY-02720

Anti-PTS Antibody (6H822) 是一种 Mouse 抗体，靶向 PTS。Anti-PTS Antibody (6H822) 可用于 ELISA。

Anti-PTS Antibody (6H822)

还可以

产品编号 TMAY-02720

Anti-PTS Antibody (6H822) 是一种 Mouse 抗体，靶向 PTS。Anti-PTS Antibody (6H822) 可用于 ELISA。

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生物活性

产品描述	Anti-PTS Antibody (6H822) is a Mouse antibody targeting PTS. Anti-PTS Antibody (6H822) can be used in ELISA.
Ig Type	Monoclonal Mouse IgG1
克隆号	6H822
交叉反应	Human
应用	ELISA
推荐剂量	ELISA: 1:1000-1:2000
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PTS (rh PTS; TMPY-03452; Q03393; Met1-Glu145). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	PTS(6-pyruvoyltetrahydropterin synthase) belongs to the PTPS family. It catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. PTS is involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. PTS also catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. Defects in PTS are the cause of BH4-deficient hyperphenylalaninemia type A (HPABH4A), also called 6-pyruvoyl-tetrahydropterin synthase deficiency (PTS deficiency) or hyperphenylalaninemia tetrahydrobiopterin-deficient due to PTS deficiency. HPABH4A is an autosomal recessive disorder characterized by depletion of the neurotransmitters dopamine and serotonin, and clinically by severe neurological symptoms unresponsive to the classic phenylalanine-low diet.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human PTS Protein (TMPY-03452)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.