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Anti-Latency-associated peptide Polyclonal Antibody

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货号 TMAB-08233

Anti-Latency-associated peptide Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Latency-associated peptide。Anti-Latency-associated peptide Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Latency-associated peptide Polyclonal Antibody

Anti-Latency-associated peptide Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08233

Anti-Latency-associated peptide Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Latency-associated peptide。Anti-Latency-associated peptide Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Latency-associated peptide Polyclonal Antibody is a Rabbit antibody targeting Latency-associated peptide. Anti-Latency-associated peptide Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Latency-associated peptide
抗原种属
Human
基因名称
TGFB1
基因ID
7040
蛋白名称
Transforming growth factor beta-1 proprotein
Uniprot ID
P01137
功能
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
化学信息
分子量Theoretical: 30/44 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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