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Anti-ART4/CD297 Antibody (8Y723) 是一种 Mouse 抗体,靶向 ART4/CD297。Anti-ART4/CD297 Antibody (8Y723) 可用于 IHC-P。
Anti-ART4/CD297 Antibody (8Y723) 是一种 Mouse 抗体,靶向 ART4/CD297。Anti-ART4/CD297 Antibody (8Y723) 可用于 IHC-P。
产品描述 | Anti-ART4/CD297 Antibody (8Y723) is a Mouse antibody targeting ART4/CD297. Anti-ART4/CD297 Antibody (8Y723) can be used in IHC-P. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 8Y723 |
交叉反应 | Rat |
验证活性 | 1. Immunochemical staining of rat ART4 in rat kidney with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of rat ART4 in rat liver with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:50-1:200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD297 (rR CD297; TMPY-03312; NP_001166980.1; Met1-Lys269). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier molecule and CD297, is a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. ART4 could be detected on HEL cells and erythrocytes by FACS analysis while it was absent from activated monocytes, despite the presence of ART4 mRNA in these cells. ART is also known as the carrier of the Dombrock blood group alloantigens (Do) which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. |
偶联 | Unconjugated |
免疫原 | Recombinant Rat CD297 Protein (TMPY-03312) |
抗原种属 | Rat |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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