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S100A9 Protein, Mouse, Recombinant (His)

S100A9 Protein, Mouse, Recombinant (His)

产品编号 TMPY-02821
别名: Cagb, MRP14, AW546964, 60B8Ag, BEE22, S100 calcium binding protein A9, L1Ag, p14, GAGB

S100A9 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15 kDa and the accession number is P31725.

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S100A9 Protein, Mouse, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 5日内发货
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产品目录号及名称: S100A9 Protein, Mouse, Recombinant (His) (TMPY-02821)
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生物活性 Testing in progress
产品描述 S100A9 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15 kDa and the accession number is P31725.
种属 Mouse
表达系统 E. coli
标签 N-His
蛋白编号 P31725
别名 Cagb, MRP14, AW546964, 60B8Ag, BEE22, S100 calcium binding protein A9, L1Ag, p14, GAGB
蛋白构建 The Mouse S100A9 (P31725) (Aal 2-Lys 113) was expressed, with a polyhistidine tag at the N-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 15 kDa (predicted)
内毒素 Please contact us for more information.
缓冲液 Supplied as sterile PBS, 1 mM DTT, 20% glycerol, pH 7.5.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calciumbinding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a proinflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

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Keywords

S100A9 Protein, Mouse, Recombinant (His) Cagb MRP14 AW546964 AW 546964 BEE-22 MRP 14 60B8Ag BEE22 S100 calcium binding protein A9 L1Ag MRP-14 p14 AW-546964 GAGB BEE 22 recombinant recombinant-proteins proteins protein

 

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