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Anti-ERCC1 Antibody (5M521)

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货号 TMAB-05658

Anti-ERCC1 Antibody (5M521) 是一种 Rabbit 抗体，靶向 ERCC1。Anti-ERCC1 Antibody (5M521) 可用于 IHC-P,IHC-Fr,IF。

Anti-ERCC1 Antibody (5M521)

Anti-ERCC1 Antibody (5M521)

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Rating icon 还可以
货号 TMAB-05658

Anti-ERCC1 Antibody (5M521) 是一种 Rabbit 抗体，靶向 ERCC1。Anti-ERCC1 Antibody (5M521) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-ERCC1 Antibody (5M521) is a Rabbit antibody targeting ERCC1. Anti-ERCC1 Antibody (5M521) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
5M521
反应种属
Human,Mouse (predicted:Rat)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009]
抗原信息
基因名称
ERCC1
基因ID
2067
蛋白名称
DNA excision repair protein ERCC-1
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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