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Anti-RBP4 Antibody (1C724) 是一种 Mouse 抗体,靶向 RBP4。Anti-RBP4 Antibody (1C724) 可用于 WB,IP,IF,IHC-P。
Anti-RBP4 Antibody (1C724) 是一种 Mouse 抗体,靶向 RBP4。Anti-RBP4 Antibody (1C724) 可用于 WB,IP,IF,IHC-P。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,985 | 5日内发货 | |
100 μL | ¥ 2,985 | 5日内发货 |
产品描述 | Anti-RBP4 Antibody (1C724) is a Mouse antibody targeting RBP4. Anti-RBP4 Antibody (1C724) can be used in WB,IP,IF,IHC-P. |
别名 | Retinol-Binding Protein 4, RBP4, RBP, PRBP, Plasma Retinol-Binding Protein |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of RBP expression in HepG2 whole cell lysate. 2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing membrane staining of hepatocytes. |
应用 | |
推荐剂量 | WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity. |
偶联 | Unconjugated |
免疫原 | Amino acids 1-201 of RBP of human origin |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 25 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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