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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-KDM5B Polyclonal Antibody

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货号 TMAB-07980

Anti-KDM5B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KDM5B。Anti-KDM5B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-KDM5B Polyclonal Antibody

Anti-KDM5B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07980

Anti-KDM5B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KDM5B。Anti-KDM5B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-KDM5B Polyclonal Antibody is a Rabbit antibody targeting KDM5B. Anti-KDM5B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,GuineaPig)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Ubiquitously expressed, with highest levels in testis. Down-regulated in melanoma and glioblastoma. Up-regulated in breast cancer (at protein level).
组织特异性Ubiquitously expressed, with highest levels in testis. Down-regulated in melanoma and glioblastoma. Up-regulated in breast cancer (at protein level).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KDM5B/PLU1/Jarid1B
抗原种属
Human
基因名称
KDM5B
基因ID
10765
蛋白名称
Lysine-specific demethylase 5B
Uniprot ID
Q9UGL1
功能
Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.
化学信息
分子量Theoretical: 170 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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