Anti-CD74 Antibody (3H62)

Name: Anti-CD74 Antibody (3H62)
Brand: TargetMol
SKU: TMAY-01630
Rating: 4.5 (1 reviews)

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产品编号 TMAY-01630

Anti-CD74 Antibody (3H62) 是一种 Mouse 抗体，靶向 CD74。Anti-CD74 Antibody (3H62) 可用于 IHC-P,FCM。

Anti-CD74 Antibody (3H62)

还可以

产品编号 TMAY-01630

Anti-CD74 Antibody (3H62) 是一种 Mouse 抗体，靶向 CD74。Anti-CD74 Antibody (3H62) 可用于 IHC-P,FCM。

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生物活性

产品描述	Anti-CD74 Antibody (3H62) is a Mouse antibody targeting CD74. Anti-CD74 Antibody (3H62) can be used in IHC-P,FCM.
Ig Type	Monoclonal Mouse IgG1
克隆号	3H62
交叉反应	Human
验证活性	1. Immunochemical staining of human CD74 in human tonsil with mouse monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CD74 in human colon carcinoma with mouse monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human CD74 in human appendix with mouse monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). 4. Flow cytometric analysis of Human CD74 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD74, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用	IHC-P,FCM
推荐剂量	IHC-P: 1:500-1:2000; FCM: 1:25-1:100
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD74 (rh CD74; TMPY-01199; NP_004346.1; Gln73-Met232). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD74, also known as HLA class2 histocompatibility antigen gamma chain and HLA-DR antigens-associated invariant chain, is a polypeptide involved in the formation and transport of MHC class2 protein. CD74 is expressed by B cells, macrophages, and Reed-Sternberg cells. When MHC class 2 protein was in the rough ER, its peptide-binding cleft was blocked by CD74 to prevent it from interacting with the endogenous peptides. CD74 also serves to facilitate MHC class2's export from ER.

偶联与修饰

偶联	Unconjugated
其他可选修饰符	APC/PE
可提供抗体种类	3

抗原信息

免疫原	Recombinant Human CD74 protein (TMPY-01199)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.