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Anti-DR6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DR6。Anti-DR6 Polyclonal Antibody 可用于 WB。
Anti-DR6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DR6。Anti-DR6 Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,160 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 | |
200 μL | ¥ 2,795 | 5日内发货 |
产品描述 | Anti-DR6 Polyclonal Antibody is a Rabbit antibody targeting DR6. Anti-DR6 Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Mouse,Rat (predicted:Human,Chicken,Dog,Cow,Horse,Rabbit) |
验证活性 | 1. Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-DR6 (TMAB-00568) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52/68 kDa Observed band size: 52 kDa 2. Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-DR6 (TMAB-00568) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52/68 kDa Observed band size: 52 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Membrane; Single-pass type I membrane protein (Probable). |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). Tissue specificity: Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes. |
免疫原 | KLH conjugated synthetic peptide: human DR6/CD358 |
抗原种属 | Human |
基因ID | |
Uniprot ID |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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