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Anti-ADAM18 Polyclonal Antibody

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货号 TMAB-02285

Anti-ADAM18 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ADAM18。Anti-ADAM18 Polyclonal Antibody 可用于 WB。

Anti-ADAM18 Polyclonal Antibody

Anti-ADAM18 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02285

Anti-ADAM18 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ADAM18。Anti-ADAM18 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-ADAM18 Polyclonal Antibody is a Rabbit antibody targeting ADAM18. Anti-ADAM18 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Dog)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Expressed specifically in testis.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ADAM18 was first described as tMDC III (testis-specific Metalloproteinase-like disintergin-like cysteine-rich protein-III). ADAM18 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the fill-length ADAM18 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a short spacer region, then the transmembrane domain and a cytoplasmic domain. Like many of the reproductive-specific ADAMS, ADAM18 plays a nonenzymatic role, or (as is the case for ADAMs 1 & 2 (fertilin alpha and beta)), the protein acts in concert with a proteolytically active ADAM to process proteins. Little is known about interactions between ADAM18 and other ADAMs. To date, 4 different sequences for human ADAM18 are published; 739, 715, 182 and 153 amino acids in length.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADAM18
抗原种属
Human
基因名称
ADAM18
基因ID
蛋白名称
Disintegrin and metalloproteinase domain-containing protein 18
功能
Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein.
化学信息
分子量Theoretical: 62 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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