购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Nucleolin/C23 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09672

Anti-Nucleolin/C23 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Nucleolin/C23。Anti-Nucleolin/C23 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-Nucleolin/C23 Polyclonal Antibody

Anti-Nucleolin/C23 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09672

Anti-Nucleolin/C23 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Nucleolin/C23。Anti-Nucleolin/C23 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-Nucleolin/C23 Polyclonal Antibody is a Rabbit antibody targeting Nucleolin/C23. Anti-Nucleolin/C23 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus, nucleolus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Nucleolin is the major nucleolar protein of growing eukaryotic cells. C23 (nucleolin, NCL) is a eukaryotic nucleolar phosphoprotein that influences synthesis and maturation of ribosomes. C23 localizes to dense fibrillar regions of the nucleolus. It contains four RNA binding domains that interact with pre-rRNA during synthesis. C23 can influence RNA processing, ribosomal gene transcription and nucleolar targeting of ribosomal components. It is known to associate with a variety of proteins, including the nucleolar protein B23. Phosphorylation by Cdc2 and casein kinase II causes translocation of C23 from the nucleolus to the cytoplasm. Mitotic phosphorylated forms of Bcl-2 are present in nuclear structures in prophase Hela cells together with C23 and Ki-67. Retinoic acid-induced apoptosis leads to C23 down-regulation and Bcl-2 mRNA instability. C23 binds the human telomerase reverse transcriptase subunit (TERT) through interactions with its RNA binding domain 4 and carboxyl-terminal RGG domain, and this interaction is critical for the nucleolar localization of human TERT.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Nucleolin
抗原种属
Human
基因名称
NCL
基因ID
4691
蛋白名称
Nucleolin
Uniprot ID
P19338
功能
Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
化学信息
分子量Theoretical: 76 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-Nucleolin/C23 Polyclonal Antibody | purchase Anti-Nucleolin/C23 Polyclonal Antibody | Anti-Nucleolin/C23 Polyclonal Antibody cost | order Anti-Nucleolin/C23 Polyclonal Antibody | Anti-Nucleolin/C23 Polyclonal Antibody molecular weight