- 全部删除
- 您的购物车当前为空
Anti-HTR2C Antibody (5H488) 是一种 Rabbit 抗体,靶向 HTR2C。Anti-HTR2C Antibody (5H488) 可用于 WB,IHC。
Anti-HTR2C Antibody (5H488) 是一种 Rabbit 抗体,靶向 HTR2C。Anti-HTR2C Antibody (5H488) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-HTR2C Antibody (5H488) is a Rabbit antibody targeting HTR2C. Anti-HTR2C Antibody (5H488) can be used in WB,IHC. |
别名 | Serotonin receptor 2C, Serotonin 5-HT-2C receptor, serotonin 2c receptor, serotonin 1c receptor, HTR2C, Htr1c, 5-hydroxytryptamine(serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 1C, 5Hydroxytryptamine 2C receptor, 5-HTR2C, 5HTR2C, 5-HT-2C, 5-HT2C, 5HT2C, 5-HT-1C receptor, 5-HT1C, 5 Hydroxytryptamine 2C receptor |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of 5HT2C Receptor on A431 (1) AND K562 (2) lysates using anti-5HT2C Receptor antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-5HT2C Receptor antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 70 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容