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7-Hydroxyflavanone

Name: 7-Hydroxyflavanone
Brand: TargetMol
SKU: T7999
Price: 117 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: 7-羟基黄烷酮

货号 T7999Cas号 6515-36-2 一键复制产品信息纯度: 99.81%

很棒

7-Hydroxyflavanone 对肺炎链球菌临床分离株显示出抗菌活性。

7-Hydroxyflavanone

一键复制产品信息

很棒

纯度: 99.81%

货号 T7999Cas号 6515-36-2

别名 7-羟基黄烷酮

7-Hydroxyflavanone 对肺炎链球菌临床分离株显示出抗菌活性。

规格	价格	库存
10 mg	¥ 137	现货
25 mg	¥ 198	现货
50 mg	¥ 289	现货
100 mg	¥ 413	现货
500 mg	¥ 997	现货
1 mL x 10 mM (in DMSO)	¥ 117	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

凭借在化合物合成方面的丰富经验，我们可以根据您的研究需求为该产品提供快速定制合成服务。

实验操作小课堂

常见问题解答

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纯度: 99.81%

颜色: 白色至黄色

性状: Solid

资源下载: COA HNMR HPLC产品操作手册

产品介绍

7-Hydroxyflavanone AI Summary

7-Hydroxyflavanone exhibits a broad range of bioactivities across various biological systems. It inhibits hamster liver mitochondrial monoamine oxidase (MAO) with an IC50 value of 13000.0 nM and demonstrates significant potency as an aromatase inhibitor in human placental microsomes, with an IC50 value of 3800.0 nM. Additionally, it shows relative activity against aminogluthetimide with a relative activity of 1.4. In bovine thymocytes, 7-Hydroxyflavanone inhibits protein tyrosine kinase with an ID50 value greater than 500.0 ug/mL. It also increases EGR1 mRNA expression in human HEK293 cells at 20 ug/mL after 6 to 12 hours, achieving a fold change of 2.1. The compound displays binding affinity to Enterococcus faecalis KAS3, with an activity value of 8.79 x 10^2/M, indicating a potential interaction with this target protein. Moreover, 7-Hydroxyflavanone is noted for various other bioactivities, including modulation of mitochondrial dynamics, miRNA regulation (specifically miR-21), re-activation of p53, inhibition of malaria parasite plastid delayed death, inverse agonism of the GLP-1 receptor, and activation of BRCA1 expression. Furthermore, it possesses antifungal properties, showing moderate antifungal potency against different fungal isolates, with a notably strong activity against Diaporthe longicolla isolate CE117, where it has a MIC value of 6.25 ug/mL..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates.
别名	7-羟基黄烷酮

化学信息

分子量	240.25
分子式	C₁₅H₁₂O₃
CAS No.	6515-36-2
Smiles	Oc1ccc2C(=O)CC(Oc2c1)c1ccccc1
密度	1.288g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 25 mg/mL (104.06 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1623 mL	20.8117 mL	41.6233 mL	208.1165 mL
5 mM	0.8325 mL	4.1623 mL	8.3247 mL	41.6233 mL
10 mM	0.4162 mL	2.0812 mL	4.1623 mL	20.8117 mL
20 mM	0.2081 mL	1.0406 mL	2.0812 mL	10.4058 mL
50 mM	0.0832 mL	0.4162 mL	0.8325 mL	4.1623 mL
100 mM	0.0416 mL	0.2081 mL	0.4162 mL	2.0812 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。